Completion of Plague's End, recipe purchased from Lady Meilyr or a Harmony pillar farmer (1,500,000 coins), and 107 Herblore to make (Exp: 750 or 900).

Player Made (See Notes).

Consumed to increase combat skills (Ranged, Magic, Defence, Attack, and Strength) by 17% +5, restore 595 Prayer points over time and 317 instantly, provide full protection from both dragon and wyvern fire, and reduce poison damage for almost 6 minutes.